| Copa de la Liga 2022 | ||||
| Fase Grupal | ||||
| 1š Fecha | ||||
| 10-feb-2022 | Parana | Patronato | 0 | |
| Argentinos Juniors | 1 | Nuss | ||
| 10-feb-2022 | Junin | Sarmiento | 1 | Lopez |
| Atletico Tucuman | 0 | |||
| 10-feb-2022 | Rosario | Newell's Old Boys | 1 | Gonzalez |
| Defensa y Justicia | 0 | |||
| 10-feb-2022 | Santiago | Central Cordoba | 3 | Lopez, Algaraņaz, Martinez |
| del Estero | Barracas Central | 1 | Bandiera | |
| 11-feb-2022 | Avellaneda | Arsenal | 1 | Lomonaco |
| Rosario Central | 1 | Ruben | ||
| 11-feb-2022 | Buenos Aires | Velez Sarsfield | 2 | Orellano, Janson |
| Aldosivi | 0 | |||
| 11-feb-2022 | Mendoza | Godoy Cruz | 1 | Ferrari |
| Tigre | 1 | Blondel | ||
| 11-feb-2022 | Lomas de Zamora | Banfield | 0 | |
| San Lorenzo | 0 | |||
| 12-feb-2022 | Buenos Aires | Huracan | 1 | Coccaro |
| Lanus | 0 | |||
| 12-feb-2022 | Santa Fe | Union | 1 | Luna (P) |
| River Plate | 0 | |||
| 12-feb-2022 | La Plata | Estudiantes | 2 | Boselli, Rogel |
| Independiente | 1 | Laso | ||
| 13-feb-2022 | Avellaneda | Racing Club | 0 | |
| Gimnasia y Esgrima | 0 | |||
| 13-feb-2022 | Vicente Lopez | Platense | 1 | Bergessio |
| Talleres | 0 | |||
| 13-feb-2022 | Buenos Aires | Boca Juniors | 1 | Benedetto |
| Colon | 1 | Beltran | ||
| 2š Fecha | ||||
| 15-feb-2022 | Buenos Aires | Argentinos Juniors | 3 | Avalos (2), Galarza |
| Newell's Old Boys | 0 | |||
| 15-feb-2022 | Rosario | Rosario Central | 1 | Baez |
| Velez Sarsfield | 0 | |||
| 15-feb-2022 | Avellaneda | Independiente | 1 | Pozzo |
| Arsenal | 0 | |||
| 15-feb-2022 | Lanus | Lanus | 2 | Lopez, Sand |
| Barracas Central | 0 | |||
| 15-feb-2022 | Buenos Aires | Huracan | 2 | Candia (2, 1P) |
| Estudiantes | 3 | Zuqui, Boselli, Diaz | ||
| 16-feb-2022 | San Fernando | Tigre | 1 | Retegui |
| Central Cordoba | 1 | Lopez | ||
| 16-feb-2022 | Mar del Plata | Aldosivi | 1 | Cauteruccio |
| Boca Juniors | 2 | Villa (2) | ||
| 16-feb-2022 | Buenos Aires | River Plate | 4 | Alvarez (3), Quintero (P) |
| Patronato | 1 | Diaz (A) | ||
| 17-feb-2022 | La Plata | Gimnasia y Esgrima | 1 | Tarragona |
| San Lorenzo | 0 | |||
| 17-feb-2022 | Santa Fe | Colon | 3 | Farias, Espinola (A), Rodriguez (P) |
| Godoy Cruz | 1 | Ojeda (P) | ||
| 17-feb-2022 | Junin | Sarmiento | 2 | Brea, Mancilla |
| Banfield | 2 | Galoppo (2) | ||
| 17-feb-2022 | Florencio Varela | Defensa y Justicia | 2 | Merentiel, Pizzini |
| Racing Club | 2 | Cardona (P), Hauche | ||
| 17-feb-2022 | San Miguel | Atletico Tucuman | 2 | Gonzales (A), Lotti |
| de Tucuman | Platense | 2 | Gomez (2) | |
| 17-feb-2022 | Cordoba | Talleres | 0 | |
| Union | 0 | |||
| 3š Fecha | ||||
| 19-feb-2022 | Avellaneda | Arsenal | 2 | Lomonaco (P), Diaz |
| Huracan | 1 | Acevedo | ||
| 19-feb-2022 | La Plata | Estudiantes | 2 | Boselli (P), Diaz |
| Lanus | 1 | Perez | ||
| 19-feb-2022 | Buenos Aires | Velez Sarsfield | 0 | |
| Independiente | 0 | |||
| 20-feb-2022 | Vicente Lopez | Platense | 2 | Bergessio (P), Contreras |
| Sarmiento | 0 | |||
| 20-feb-2022 | Buenos Aires | Boca Juniors | 2 | Izquierdoz, Fabra |
| Rosario Central | 1 | Martinez | ||
| 20-feb-2022 | Rosario | Newell's Oid Boys | 0 | |
| River Plate | 2 | Quintero, Rojas | ||
| 21-feb-2022 | Buenos Aires | Barracas Central | 0 | |
| Tigre | 2 | Magnin, Protti | ||
| 21-feb-2022 | Lomas de Zamora | Banfield | 4 | Alvarez, Urzi, Cruz (P), Datolo (P) |
| Gimnasia y Esgrima | 0 | |||
| 21-feb-2022 | Mendoza | Godoy Cruz | 0 | |
| Aldosivi | 2 | Cauteruccio, Pisano | ||
| 21-feb-2022 | Buenos Aires | San Lorenzo | 3 | Martegani, Zapata, Soto (A) |
| Defensa y Justicia | 4 | Bou, Merentiel, Rotondi, Pizzini | ||
| 22-feb-2022 | Parana | Patronato | 0 | |
| Talleres | 0 | |||
| 22-feb-2022 | Santa Fe | Union | 1 | Alvez |
| Atletico Tucuman | 0 | |||
| 22-feb-2022 | Avellaneda | Racing Club | 3 | Correa, Alcaraz, Copetti |
| Argentinos Juniors | 0 | |||
| 22-feb-2022 | Santiago | Central Cordoba | 0 | |
| del Estero | Colon | 2 | Rodriguez, Garces | |
| 4š Fecha | ||||
| 24-feb-2022 | Buenos Aires | Huracan | 2 | Candia (P), Coccaro |
| Velez Sarsfield | 0 | |||
| 25-feb-2022 | Mar del Plata | Defensa y Justicia | 3 | Merentiel, Rotondi, Tripichio |
| Gimnasia y Esgrima | 2 | Tarragona, Frias (A) | ||
| 25-feb-2022 | Vicente Lopez | Platense | 0 | |
| Banfield | 1 | Galoppo | ||
| 26-feb-2022 | Santa Fe | Colon | 2 | Bernardi, Beltran |
| Barracas Central | 1 | Ferreyra | ||
| 26-feb-2022 | Rosario | Rosario Central | 1 | Almada |
| Godoy Cruz | 2 | Ojeda, Rodriguez | ||
| 26-feb-2022 | Mar del Plata | Aldosivi | 0 | |
| Central Cordoba | 0 | |||
| 26-feb-2022 | Avellaneda | Independiente | 2 | Togni, Soņora |
| Boca Juniors | 2 | Benedetto (2, 1P) | ||
| 27-feb-2022 | Junin | Sarmiento | 2 | Torres, Andueza |
| Union | 1 | Roldan | ||
| 27-feb-2022 | La Plata | Estudiantes | 3 | Pellegrini, Diaz, Boselli |
| Arsenal | 2 | Ibaņez, Lomonaco | ||
| 27-feb-2022 | Buenos Aires | River Plate | 2 | Barco, De la Cruz |
| Racing Club | 2 | Copetti, Miranda | ||
| 27-feb-2022 | Buenos Aires | Argentinos Juniors | 1 | Zalazar |
| San Lorenzo | 1 | Centurion | ||
| 28-feb-2022 | Cordoba | Talleres | 1 | Girotti |
| Newell's Old Boys | 2 | Castro, Lema (P) | ||
| 28-feb-2022 | Lanus | Lanus | 0 | |
| Tigre | 0 | |||
| 1-mar-2022 | San Miguel | Atletico Tucuman | 1 | Andrada |
| de Tucuman | Patronato | 0 | ||
| 5š Fecha | ||||
| 3-mar-2022 | Santiago | Central Cordoba | 0 | |
| del Estero | Rosario Central | 1 | Almada | |
| 4-mar-2022 | Santa Fe | Union | 1 | Alvez |
| Platense | 0 | |||
| 4-mar-2022 | La Plata | Gimnasia y Esgrima | 2 | Aleman (2, 1P) |
| Argentinos Juniors | 2 | Carabajal, Mac Allister | ||
| 4-mar-2022 | Buenos Aires | Barracas Central | 2 | Mouche, Bandiera |
| Aldosivi | 1 | Cauteruccio | ||
| 5-mar-2022 | Buenos Aires | San Lorenzo | 0 | |
| River Plate | 1 | Diaz | ||
| 5-mar-2022 | Parana | Patronato | 0 | |
| Sarmiento | 1 | Torres | ||
| 5-mar-2022 | Avellaneda | Racing Club | 1 | Hauche |
| Talleres | 0 | |||
| 6-mar-2022 | Lomas de Zamora | Banfield | 2 | Tanco, Galoppo |
| Defensa y Justicia | 3 | Colombo, Merentiel, Fontana | ||
| 6-mar-2022 | Rosario | Newell's Old Boys | 4 | Garro, Castro, Sordo, Funez |
| Atletico Tucuman | 0 | |||
| 6-mar-2022 | Buenos Aires | Boca Juniors | 0 | |
| Huracan | 1 | Coccaro | ||
| 6-mar-2022 | Buenos Aires | Velez Sarsfield | 1 | Janson |
| Estudiantes | 1 | Diaz | ||
| 7-mar-2022 | Mendoza | Godoy Cruz | 3 | Bullaude (2), Ojeda (P) |
| Independiente | 3 | Benavidez, Marquez, Benegas | ||
| 7-mar-2022 | Avellaneda | Arsenal | 1 | Brochero, Kruspzky |
| Lanus | 1 | Lopez, Aguirre | ||
| 7-mar-2022 | San Fernando | Tigre | 1 | Castro |
| Colon | 0 | |||
| 6š Fecha | ||||
| 11-mar-2022 | Avellaneda | Arsenal | 0 | |
| Velez Sarsfield | 0 | |||
| 11-mar-2022 | Vicente Lopez | Platense | 1 | Canteros |
| Patronato | 2 | Mosevich, Castro | ||
| 12-mar-2022 | Mar del Plata | Aldosivi | 1 | Meli |
| Tigre | 0 | |||
| 12-mar-2022 | Buenos Aires | Huracan | 1 | Candia |
| Godoy Cruz | 3 | Bullaude, Rodriguez, Ojeda | ||
| 12-mar-2022 | Junin | Sarmiento | 2 | Toledo, Torres (P) |
| Newell's Old Boys | 2 | Garcia, Sforza | ||
| 12-mar-2022 | Rosario | Rosario Central | 1 | Ruben (P) |
| Barracas Central | 3 | Arce, Sepulveda, Castro | ||
| 12-mar-2022 | Cordoba | Talleres | 0 | |
| San Lorenzo | 1 | Gordillo | ||
| 13-mar-2022 | Santa Fe | Union | 2 | Polenta, Lollo (A) |
| Banfield | 1 | Enrique | ||
| 13-mar-2022 | Lanus | Lanus | 1 | Perez |
| Colon | 1 | Beltran | ||
| 13-mar-2022 | Buenos Aires | River Plate | 4 | Fernandez (P), Alvarez (P), Quintero (P), Romero |
| Gimnasia y Esgrima | 0 | |||
| 13-mar-2022 | La Plata | Estudiantes | 0 | |
| Boca Juniors | 1 | Advincula | ||
| 14-mar-2022 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | Racing Club | 4 | Mura, Alcaraz, Miranda, Martinez | |
| 14-mar-2022 | Buenos Aires | Argentinos Juniors | 0 | |
| Defensa y Justicia | 1 | Galvan | ||
| 14-mar-2022 | Avellaneda | Independiente | 1 | Roa |
| Central Cordoba | 1 | Gonzalez | ||
| 7š Fecha | ||||
| 18-mar-2022 | Mar del Plata | Aldosivi | 3 | Cauteruccio (2, 1P), Silva |
| Patronato | 1 | Barrios (P) | ||
| 18-mar-2022 | San Fernando | Tigre | 4 | Colidio, Magnin (2, 1P), Blondel |
| Platense | 0 | |||
| 18-mar-2022 | Buenos Aires | Barracas Central | 2 | Bandiera, Ferreyra |
| Sarmiento | 1 | Toledo | ||
| 19-mar-2022 | Lanus | Lanus | 0 | |
| Banfield | 1 | Lollo | ||
| 19-mar-2022 | Buenos Aires | San Lorenzo | 0 | |
| Huracan | 0 | |||
| 19-mar-2022 | Santa Fe | Colon | 0 | |
| Union | 0 | |||
| 19-mar-2022 | Avellaneda | Independiente | 1 | Gonzalez |
| Racing Club | 2 | Hauche, Copetti | ||
| 20-mar-2022 | Rosario | Rosario Central | 0 | |
| Newell's Old Boys | 1 | Garcia | ||
| 20-mar-2022 | La Plata | Gimnasia y Esgrima | 1 | Ramirez |
| Estudiantes | 1 | Godoy | ||
| 20-mar-2022 | Buenos Aires | River Plate | 0 | |
| Boca Juniors | 1 | Villa | ||
| 21-mar-2022 | Mar del Plata | Defensa y Justicia | 1 | Frias (P) |
| Arsenal | 1 | Goņi | ||
| 21-mar-2022 | Buenos Aires | Argentinos Juniors | 1 | Vera |
| Velez Sarsfield | 0 | |||
| 22-mar-2022 | San Miguel | Atletico Tucuman | 0 | |
| de Tucuman | Central Cordoba | 1 | Riaņo | |
| 22-mar-2022 | Cordoba | Talleres | 2 | Mendez, Valoyes |
| Godoy Cruz | 1 | Rodriguez | ||
| 8š Fecha | ||||
| 31-mar-2022 | Santa Fe | Colon | 1 | Beltran |
| Aldosivi | 3 | Cauteruccio (P), Mosquera, Pisano | ||
| 1-abr-2022 | La Plata | Gimnasia y Esgrima | 2 | Tarragona, Aleman |
| Talleres | 1 | Esquivel | ||
| 1-abr-2022 | Parana | Patronato | 2 | Barrios (2, 1P) |
| Union | 1 | Gallegos | ||
| 1-abr-2022 | Santiago | Central Cordoba | 2 | Riaņo, Lopez |
| del Estero | Huracan | 2 | Coccaro, Cristaldo | |
| 1-abr-2022 | Lomas de Zamora | Banfield | 0 | |
| Atgentinos Juniors | 2 | Cabrera, Gomez | ||
| 1-abr-2022 | Buenos Aires | Barracas Central | 0 | |
| Independiente | 1 | Pozzo | ||
| 2-abr-2022 | Avellaneda | Racing Club | 4 | Copetti (2), Chancalay (P), Correa |
| Sarmiento | 1 | Brea | ||
| 2-abr-2022 | Buenos Aires | Velez Sarsfield | 3 | Janson (2), Pratto |
| Lanus | 1 | Pasquini | ||
| 2-abr-2022 | Mendoza | Godoy Cruz | 3 | Bullaude (2), Ojeda (P) |
| Estudiantes | 3 | Rogel, Spetale, Zapiola (P) | ||
| 2-abr-2022 | Florencio Varela | Defensa y Justicia | 1 | Bou |
| River Plate | 2 | Fernandez, Simon | ||
| 2-abr-2022 | Buenos Aires | Boca Juniors | 1 | Vazquez, Rojo (P) |
| Arsenal | 2 | Lomonaco, Colman | ||
| 3-abr-2022 | Buenos Aires | San Lorenzo | 1 | Centurion |
| Atletico Tucuman | 1 | Carrera | ||
| 3-abr-2022 | Rosario | Newell's Old Boys | 3 | Garro, Castro (P), Reasco |
| Platense | 1 | Schor | ||
| 3-abr-2022 | San Fernando | Tigre | 2 | Magnin (P), Blondel |
| Rosario Central | 0 | |||
| 9š Fecha | ||||
| 8-abr-2022 | San Miguel | Atletico Tucuman | 1 | Ortiz |
| de Tucuman | Gimnasia y Esgrima | 2 | Tarragona (2, 1P) | |
| 8-abr-2022 | Avellaneda | Arsenal | 3 | Lomonaco (P), Kruspzky, Gariglio |
| Godoy Cruz | 3 | Ferrari, Suarez (A), Ortiz | ||
| 8-abr-2022 | Junin | Sarmiento | 2 | Torres (2, 1P) |
| San Lorenzo | 1 | Ortigoza (P) | ||
| 8-abr-2022 | Rosario | Rosario Central | 2 | Ojeda, Ferreyra |
| Colon | 2 | Pierotti, Abila | ||
| 9-abr-2022 | Santa Fe | Union | 1 | Gonzalez (P) |
| Newell's Old Boys | 2 | |||
| 9-abr-2022 | Cordoba | Talleres | 1 | Santos |
| Defensa y Justicia | 5 | Rotondi, Fernandez (2), Merentiel, Alanis | ||
| 9-abr-2022 | Avellaneda | Independiente | 1 | Benegas (P) |
| Tigre | 1 | Retegui | ||
| 9-abr-2022 | Buenos Aires | Velez Sarsfield | 0 | |
| Boca Juniors | 0 | |||
| 10-abr-2022 | Parana | Patronato | 0 | |
| Banfield | 1 | Galoppo | ||
| 10-abr-2022 | La Plata | Estudiantes | 5 | Boselli (3), Diaz, Del Prete |
| Central Cordoba | 0 | |||
| 10-abr-2022 | Parana | Platense | 0 | |
| Racing Club | 1 | Cardona (P) | ||
| 10-abr-2022 | Buenos Aires | River Plate | 4 | Suarez, Fernandez, Quintero (P), Herrera |
| Argentinos Juniors | 2 | Avalos, Villalba | ||
| 11-abr-2022 | Buenos Aires | Huracan | 1 | Cristaldo |
| Barracas Central | 2 | Ferreyra, Tapia | ||
| 11-abr-2022 | Lanus | Lanus | 1 | Acosta |
| Aldosivi | 2 | Cauteruccio, Maciel | ||
| 10š Fecha | ||||
| 14-abr-2022 | La Plata | Gimnasia y Esgrima | 1 | Andueza (A) |
| Sarmiento | 3 | Arismendi, Gondou, Mainero | ||
| 15-abr-2022 | San Fernando | Tigre | 2 | Magnin (P), Flores |
| Huracan | 1 | Cordero | ||
| 15-abr-2022 | Santiago | Central Cordoba | 3 | Riaņo, Gonzalez, Lopez |
| del Estero | Arsenal | 3 | Colman, Goņi, Lomonaco | |
| 15-abr-2022 | Mar del Plata | Aldosivi | 1 | Cauteruccio (P) |
| Rosario Central | 0 | |||
| 15-abr-2022 | Rosario | Newell's Old Boys | 1 | Sordo |
| Patronato | 0 | |||
| 16-abr-2022 | Buenos Aires | San Lorenzo | 2 | Gordillo, Bareiro |
| Platense | 2 | Andrade, Mansilla | ||
| 16-abr-2022 | Santa Fe | Colon | 2 | Beltran, Rodriguez |
| Independiente | 2 | Blanco, Benegas | ||
| 16-abr-2022 | Buenos Aires | Barracas Central | 1 | Tapia |
| Estudiantes | 6 | Del Prete (2), Castro, Boselli, Diaz (P), Orosco | ||
| 16-abr-2022 | Avellaneda | Racing Club | 1 | Copetti |
| Union | 0 | |||
| 17-abr-2022 | Florencio Varela | Defensa y Justicia | 1 | Merentiel |
| Atletico Tucuman | 1 | Lotti | ||
| 17-abr-2022 | Mendoza | Godoy Cruz | 0 | |
| Velez Sarsfield | 0 | |||
| 17-abr-2022 | Buenos Aires | Argentinos Juniors | 2 | Martino (A), Avalos |
| Talleres | 1 | Girotti | ||
| 17-abr-2022 | Buenos Aires | Boca Juniors | 1 | Villa |
| Lanus | 1 | Sand | ||
| 17-abr-2022 | Lomas de Zamora | Banfield | 1 | Perales |
| River Plate | 2 | Fernandez (P), Suarez | ||
| 11š Fecha | ||||
| 19-abr-2022 | Avellaneda | Arsenal | 0 | |
| Barracas Central | 1 | Bandiera | ||
| 19-abr-2022 | Santa Fe | Union | 1 | Bucca |
| San Lorenzo | 2 | Gattoni (2) | ||
| 19-abr-2022 | Buenos Aires | Huracan | 1 | Galvan |
| Colon | 1 | Farias (P) | ||
| 19-abr-2022 | La Plata | Estudiantes | 2 | Zapiola, Boselli |
| Tigre | 1 | Demartini | ||
| 19-abr-2022 | Parana | Platense | 0 | |
| Gimnasia y Esgrima | 3 | Tarragona (P), Sosa (P), Ramirez | ||
| 19-abr-2022 | Avellaneda | Independiente | 1 | Pozzo |
| Aldosivi | 1 | Silva | ||
| 20-abr-2022 | Rosario | Newell's Old Boys | 1 | Garcia (P) |
| Banfield | 0 | |||
| 20-abr-2022 | Parana | Patronato | 2 | Castro, Rodriguez |
| Racing Club | 3 | Correa (2), Rojas (P) | ||
| 20-abr-2022 | Buenos Aires | Velez Sarsfield | 1 | Orellano |
| Central Cordoba | 2 | Lopez, Bay | ||
| 20-abr-2022 | Cordoba | Talleres | 1 | Valoyes |
| River Plate | 0 | |||
| 20-abr-2022 | Lanus | Lanus | 3 | Lopez, Valeri, Gonzalez |
| Rosario Central | 1 | Benitez | ||
| 20-abr-2022 | Buenos Aires | Boca Juniors | 1 | Benedetto (P) |
| Godoy Cruz | 1 | Rodriguez | ||
| 21-abr-2022 | Junin | Sarmiento | 2 | Brea, Arismendi |
| Defensa y Justicia | 1 | Ayala (A) | ||
| 21-abr-2022 | San Miguel | Atletico Tucuman | 2 | Bianchi, Tesuri |
| de Tucuman | Argentinos Juniors | 4 | Avalos, Mac Allister, Veron, Capasso (A) | |
| 12š Fecha | ||||
| 22-abr-2022 | Santa Fe | Colon | 2 | Bernardi, Rodriguez |
| Estudiantes | 2 | Morel, Kociubinski | ||
| 23-abr-2022 | La Plata | Gimnasia y Esgrima | 1 | Sosa |
| Union | 0 | |||
| 23-abr-2022 | Buenos Aires | San Lorenzo | 1 | Ojeda (A) |
| Patronato | 2 | Rodriguez, Gudiņo | ||
| 23-abr-2022 | Rosario | Rosario Central | 3 | Ruven, Velazquez, Montoya |
| Independiente | 0 | |||
| 23-abr-2022 | Santiago | Central Cordoba | 1 | Lopez (P) |
| del Estero | Boca Juniors | 2 | Salvio (2) | |
| 23-abr-2022 | Lomas de Zamora | Banfield | 3 | Cvitanich, Lollo, Urzi |
| Talleres | 1 | Santos | ||
| 23-abr-2022 | Buenos Aires | Barracas Central | 1 | Mouche |
| Velez Sarsfield | 1 | Janson (P) | ||
| 24-abr-2022 | Avellaneda | Racing Club | 0 | |
| Newell's Old Boys | 0 | |||
| 24-abr-2022 | Buenos Aires | River Plate | 1 | Fernandez (P) |
| Atletico Tucuman | 1 | Ruiz | ||
| 24-abr-2022 | Florencio Varela | Defensa y Justicia | 1 | Merentiel |
| Platense | 1 | Canteros | ||
| 24-abr-2022 | Mendoza | Godoy Cruz | 1 | Rodriguez |
| Lanus | 1 | Ortiz (A) | ||
| 25-abr-2022 | San Fernando | Tigre | 0 | |
| Arsenal | 0 | |||
| 25-abr-2022 | Buenos Aires | Argentinos Juniors | 0 | |
| Sarmiento | 0 | |||
| 25-abr-2022 | Mar del Plata | Aldosivi | 0 | |
| Huracan | 2 | Coccaro (2) | ||
| 13š Fecha | ||||
| 27-abr-2022 | Rosario | Newell's Old Boys | 1 | Lema |
| San Lorenzo | 2 | Martegani, Gattoni | ||
| 29-abr-2022 | La Plata | Estudiantes | 2 | Castro, Morel |
| Aldosivi | 1 | Meli | ||
| 29-abr-2022 | Parana | Patronato | 0 | |
| Gimnasia y Esgrima | 6 | Aleman (2), Tarragona (2), Carbonero, Ramirez | ||
| 30-abr-2022 | San Miguel | Atletico Tucuman | 3 | Palacios (A), Menendez (2, 1P) |
| de Tucuman | Talleres | 0 | ||
| 30-abr-2022 | Avellaneda | Racing Club | 1 | Dominguez |
| Banfield | 1 | Quiroz (A) | ||
| 30-abr-2022 | Buenos Aires | Velez Sarsfield | 3 | Florentin, Janson (P), Fernandez |
| Tigre | 2 | Obando, Prieto | ||
| 30-abr-2022 | Avellaneda | Arsenal | 2 | Colman, Lomonaco |
| Colon | 0 | |||
| 30-abr-2022 | Buenos Aires | Boca Juniors | 2 | Benedetto (2) |
| Barracas Central | 0 | |||
| 30-abr-2022 | Junin | Sarmiento | 0 | |
| River Plate | 7 | Pochettino, Alvarez (3), Fernandez, Barco, Simon | ||
| 30-abr-2022 | Lanus | Lanus | 1 | Gonzalez |
| Independiente | 0 | |||
| 2-may-2022 | Santa Fe | Union | 1 | Peralta |
| Defensa y Justicia | 2 | Rotondi, Pizzini | ||
| 2-may-2022 | Mendoza | Godoy Cruz | 1 | Ojeda |
| Central Cordoba | 0 | |||
| 2-may-2022 | Vicente Lopez | Platense | 1 | Mansilla |
| Argentinos Juniors | 1 | Florentin | ||
| 2-may-2022 | Buenos Aires | Huracan | 2 | Coccaro (P), Cristaldo (P) |
| Rosario Central | 1 | Veliz | ||
| 14š Fecha | ||||
| 6-may-2022 | Buenos Aires | San Lorenzo | 1 | Martegani |
| Racing Club | 1 | Correa | ||
| 6-may-2022 | Buenos Aires | Barracas Central | 3 | Mouche, Sepulveda, Bandiera |
| Godoy Cruz | 1 | Bullaude | ||
| 7-may-2022 | San Fernando | Tigre | 0 | |
| Boca Juniors | 2 | Benedetto, Vazquez | ||
| 7-may-2022 | Mar del Plata | Aldosivi | 1 | Cauteruccio |
| Arsenal | 2 | Kruspzky (2) | ||
| 7-may-2022 | Avellaneda | Independiente | 3 | Soņora, Cazares, Fernandez |
| Huracan | 0 | |||
| 7-may-2022 | Rosario | Rosario Central | 3 | Ferreyra, Veliz, Ruben |
| Estudiantes | 1 | Piņeiro | ||
| 8-may-2022 | Cordoba | Talleres | 1 | Girotti |
| Sarmiento | 0 | |||
| 8-may-2022 | Buenos Aires | Argentinos Juniors | 2 | Torren (P), Mac Allister |
| Union | 1 | Gallegos | ||
| 8-may-2022 | Florencio Varela | Defensa y Justicia | 1 | Frias |
| Patronato | 0 | |||
| 8-may-2022 | La Plata | Gimnasia y Esgrima | 3 | Ramirez, Sosa (2) |
| Newell's Old Boys | 1 | Perez | ||
| 8-may-2022 | Buenos Aires | River Plate | 2 | Paradela, Alvarez (P) |
| Platense | 1 | Mansilla | ||
| 9-may-2022 | Santiago | Central Cordoba | 3 | Lopez, Linares, Martinez (P) |
| del Estero | Lanus | 3 | Malcorra, Braghiri, Lopez | |
| 9-may-2022 | Santa Fe | Colon | 1 | Abila |
| Velez Sarsfield | 2 | Osorio, Janson | ||
| 9-may-2022 | Lomas de Zamora | Banfield | 1 | Urzi |
| Atletico Tucuman | 1 | Lollo (A) | ||
| Cuartos de Final | ||||
| 10-may-2022 | Avellaneda | Racing Club | 5 | Alcaraz (2), Copetti (2, 1P), Correa |
| Aldosivi | 0 | |||
| 10-may-2022 | Buenos Aires | Boca Juniors | 2 | Villa, Ramirez |
| Defensa y Justicia | 0 | |||
| 11-may-2022 | La Plata | Estudiantes | 1(3) | Boselli |
| Argentinos Juniors | 1(4) | Vera | ||
| 11-may-2022 | Buenos Aires | River Plate | 1 | Fernandez |
| Tigre | 2 | Retegui, Colidio | ||
| Semifinales | ||||
| 14-may-2022 | Lanus | Boca Juniors | 0(6) | |
| Racing Club | 0(5) | |||
| 14-may-2022 | Buenos Aires | Tigre | 1(3) | Castro |
| Argentinos Juniors | 1(1) | Avalos | ||
| FINAL | ||||
| 22-may-2022 | Cordoba | Boca Juniors | 3 | Rojo, Fabra, Vazquez |
| Tigre | 0 | |||